EMERGENCE OF COLISTIN RESISTANCE IN KLEBSIELLA PNEUMONIAE ST15 DISSEMINATING BLAKPC-2 IN A NOVEL GENETIC PLATFORM

Emergence of colistin resistance in Klebsiella pneumoniae ST15 disseminating blaKPC-2 in a novel genetic platform

ABSTRACT: Objectives: Isolation of colistin- and carbapenem-resistant Klebsiella pneumoniae (CCR-Kp) is increasing in hospital settings worldwide, which is related to increased morbidity, mortality and healthcare costs.The aim of this work was to perform whole-genome sequencing (WGS), genomic and phylogenetic analysis, and conjugation assays of an

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Slotted shell resilient elements for drilling shock absorbers

The new design of a resilient element for application in drilling devices of vibration protection is presented.A cylindrical shell with a cut along its generatrix is the peculiarity of the proposed design.The presented resilient element has high loaded and damping properties upon cross dimension hard restriction condition.Besides, the design is sim

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Purification, Characterization and Bactericidal Action of Lysozyme, Isolated from Bacillus subtillis BSN314: A Disintegrating Effect of Lysozyme on Gram-Positive and Gram-Negative Bacteria

In the present study, lysozyme was purified by the following multi-step methodology: salt (ammonium sulfate) precipitation, dialysis, and ultrafiltration.The lysozyme potential was measured by enzymatic activity after each purification step.However, after ultrafiltration, the resulting material was considered extra purified.It was concentrated best

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Internet sourcing and unsafe use of controlled drugs (opioids, sedatives and GABA drugs) in the UK: An in depth case study of consumer dynamics during COVID-19

The Internet offers increased availability and accessibility of medicinal pharmaceuticals including those containing opioids, sedatives and gamma-aminobutyric acid (GABA) drugs through both legal and illegal routes.Sourcing concerns have been further heightened due to the current severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic w

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